Tolazoline hydrochloride ( Arterodyl; Priscoline )

Catalog No. M15232 CAS No. 59-97-2

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Product Name

Tolazoline hydrochloride
Note

Research use only, not for human use.
Brief Description

Tolazoline hydrochloride is a vasodilator that apparently has direct actions on blood vessels and also increases cardiac output.
Description

Tolazoline hydrochloride is a vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
Synonyms

Arterodyl; Priscoline
Pathway

Endocrinology/Hormones
Target

Adrenergic Receptor
Recptor

α-adrenergic receptor
Research Area

Other Indications
Indication

——

CAS Number

59-97-2
Formula Weight

196.68
Molecular Formula

C10H13ClN2
Purity

>98%(HPLC)
Solubility

Ethanol: 39 mg/mL (198.29 mM); Water: 39 mg/mL (198.29 mM); DMSO: 39 mg/mL (198.29 mM)
SMILES

[H]Cl.C1(CC2=CC=CC=C2)=NCCN1
Chemical Name

1H-Imidazole, 4,5-dihydro-2-(phenylmethyl)-, hydrochloride (1:1)

1.Lei L, et al. J Cardiovasc Pharmacol, 1998, 31(5), 721-733.

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